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Bizarre illnesses and plagues that kill people in the most unspeakable ways. Obsessive and inspired efforts by scientists to solve mysteries and save lives. From The Hot Zone to The Demon in the Freezer and beyond, Richard Preston’s bestselling works have mesmerized readers everywhere by showing them strange worlds of nature they never dreamed of. Panic in Level 4 is a grand tour through the eerie and unforgettable universe of Richard Preston, filled with incredible characters and mysteries that refuse to leave one’s mind. Here are dramatic true stories from this acclaimed and award-winning author, including: • The phenomenon of “self-cannibals,” who suffer from a rare genetic condition caused by one wrong letter in their DNA that forces them to compulsively chew their own flesh–and why everyone may have a touch of this disease. • The search for the unknown host of Ebola virus, an organism hidden somewhere in African rain forests, where the disease finds its way into the human species, causing outbreaks of unparalleled horror. • The brilliant Russian brothers–“one mathematician divided between two bodies”–who built a supercomputer in their apartment from mail-order parts in an attempt to find hidden order in the number pi (π). In fascinating, intimate, and exhilarating detail, Richard Preston portrays the frightening forces and constructive discoveries that are currently roiling and reordering our world, once again proving himself a master of the nonfiction narrative and, as noted in The Washington Post, “a science writer with an uncommon gift for turning complex biology into riveting page-turners.”
Bizarre illnesses and plagues that kill people in the most unspeakable ways. Obsessive and inspired efforts by scientists to solve mysteries and save lives. From The Hot Zone to The Demon in the Freezer and beyond, Richard Preston’s bestselling works have mesmerized readers everywhere by showing them strange worlds of nature they never dreamed of. Panic in Level 4 is a grand tour through the eerie and unforgettable universe of Richard Preston, filled with incredible characters and mysteries that refuse to leave one’s mind. Here are dramatic true stories from this acclaimed and award-winning author, including: • The phenomenon of “self-cannibals,” who suffer from a rare genetic condition caused by one wrong letter in their DNA that forces them to compulsively chew their own flesh–and why everyone may have a touch of this disease. • The search for the unknown host of Ebola virus, an organism hidden somewhere in African rain forests, where the disease finds its way into the human species, causing outbreaks of unparalleled horror. • The brilliant Russian brothers–“one mathematician divided between two bodies”–who built a supercomputer in their apartment from mail-order parts in an attempt to find hidden order in the number pi (π). In fascinating, intimate, and exhilarating detail, Richard Preston portrays the frightening forces and constructive discoveries that are currently roiling and reordering our world, once again proving himself a master of the nonfiction narrative and, as noted in The Washington Post, “a science writer with an uncommon gift for turning complex biology into riveting page-turners.”
Due to publisher restrictions the library cannot purchase additional copies of this title, and we apologize if there is a long waiting list. Be sure to check for other copies, because there may be other editions available.
Due to publisher restrictions the library cannot purchase additional copies of this title, and we apologize if there is a long waiting list. Be sure to check for other copies, because there may be other editions available.
Excerpts-
From the bookPANIC IN LEVEL 4 by Richard Preston
INTRODUCTION- Adventures in Nonfiction Writing
Oliver Heaviside, the English mathematician and physicist, once said, “In order to know soup, it is not necessary to climb into a pot and be boiled.” Unfortunately, this statement is not true for journalists. As a writer of what’s called “literary nonfiction” or “creative nonfiction”– narrative that is said to read like a novel but is factually verifiable– it has often been my practice to climb into the soup. Getting boiled with your characters is a good way to get to know them, but it has occasionally led me into frightening situations.
Some years ago, while I was researching The Hot Zone, a book that focuses on the Ebola virus, I may have had a meeting with an unknown strain of Ebola. (A virus is an exceedingly small life-form, an infectious parasite that replicates inside living cells, using the cell’s own machinery to make more copies of itself.)
Ebola has now been classified into seven different known types. Though it has been studied for more than thirty years, Ebola is one of the least-understood viruses in nature. Scientists have been understandably reluctant to study Ebola too closely because it has on occasion killed those who tried to do so. The virus was first was noticed in 1976, when it surfaced in Yambuku, Zaire (now the Democratic Republic of Congo), near the Ebola River, where it sacked a Catholic mission hospital, killing most of the medical staff along with a number of patients and people the patients had came into contact with. Ebola spreads from one person to the next by direct contact with blood or secretions, including sweat. There is no evidence that it can spread among humans through the air, although there is some evidence that it may spread among monkeys this way. As a parasite, Ebola carries on its life cycle in some unidentified type of animal–Ebola’s natural host–that lives in certain unidentified habitats in equatorial Africa. Occasionally Ebola comes into contact with a person, and the virus makes what is known as a trans-species jump from its host into the human species.
When Ebola gets inside a human host, it causes the person’s immune system to vanish, and the person dies with hemorrhages coming from the body’s orifices. The most lethal strains of Ebola have been known to kill up to 95 percent of people who become infected with it. Ebola causes people to vomit masses of black blood with a distinctive “coffee grounds” appearance. Victims can have a bright red nosebleed, or epistaxis; it won’t stop. A spotty, bumpy rash spreads over the body, while small, starlike hemorrhages appear beneath the skin. An Ebola patient can have blood standing in droplets on the eyelids and running from the tear ducts down the face. Blood can flow from the nose, mouth, vagina, rectum. The testicles can become infected with Ebola and can swell up or be destroyed. Victims display signs of psychosis. They can develop endless hiccups. Rarely, in particularly severe cases of Ebola, the linings of the intestines and rectum may come off. Those membranes may be expelled through the anus in raglike pieces called casts, or the intestinal lining can emerge in the form of a sleeve, like a sock. When an Ebola patient expels a sleeve, it is known as throwing a tubular cast.
Some of the action in The Hot Zone takes place at Fort Detrick, an Army base in the rolling country along the eastern flank of the Appalachian Mountains in Maryland, an hour’s drive northwest of Washington, D.C....
About the Author-
Richard Preston is the bestselling author of The Hot Zone, The Demon in the Freezer, The Wild Trees, and the novel The Cobra Event. A writer for The New Yorker since 1985, Preston is the only nondoctor to have received the Centers for Disease Control’s Champion of Prevention Award. He also holds an award from the American Institute of Physics. Preston lives outside of New York City. www.richardpreston.net
Reviews-
May 26, 2008 "Buffy the Vampire Slayer"'s James Lurie brings his rich, honeyed baritone to Prestons book of essays on radical science. The book is rather uneven. The first chapter is an overly self-referential account of Prestons own laboratory encounter with the Ebola virus he made famous in "The Hot Zone"; the other essays are more traditional portraits of scientists on the frontier of discovery. Lurie conjures an engaging and credible Russian accent when speaking for two immigrant mathematicians who are racing to determine all the digits of pi. But he is inconsistent and strained when attempting a genetics researchers British accent. Still, listeners will enjoy the way both Preston and Lurie uncover the humanity of great researchers, whether they are attempting to save hemlock and chestnut trees from fast-encroaching diseases or help those suffering from Lesch-Nyhan syndrome, a rare condition that causes its victims to compulsively consume their own flesh. "A Random House hardcover (reviews, Apr. 21). (June)" .
October 1, 2008 Adult/High SchoolPre-ston gets to the heart of these nonfiction essays by placing himself in the center of the story. The "panic" of the book's title refers to his own when his biohazard suit was breached and he feared he may have been exposed to one of the deadliest known viruses. Two of the pieces involve the brothers Chudnovsky, mathematicians so closely dependent on one another that they refer to themselves as The Mathematician. The author was able to disappear as an interviewer to the extent that he became part of the brothers' portrait. At one point, one Chudnovsky says to the other: "The interviewer answers our questions]. The interviewer becomes a person in the story." Preston used this skill of blending into his accounts to his advantage. Whether he was strapping on gear to climb mammoth hemlocks with arborists trying to understand the diseases killing the great trees of the world or acting as an off-road driver for a couple of men with the disease of self-cannibalization, Preston fit in like a good supporting actor who also happened to be the cameraman, writer, and director. Teens will find these stories compelling. The author has the eyes and language of a fine novelist, but he has the mind of a scientist who is trying to understand some of the most fascinating mysteries of our age."Will Marston, Berkeley Public Library, CA"
Copyright 2008 School Library Journal, LLC Used with permission.
April 21, 2008 The title of New Yorker contributor Preston’s new collection refers to the subject of his bestselling The Hot Zone : a series of rooms in a government biohazard laboratory where scientists work with virulent pathogens like the Ebola viruses that would be devastating in the hands of terrorists. The essays (all from the New Yorker ) cover such scientific matters as a profile of controversial über-genome mapper Craig Venter; a gene that leads people to cannibalize themselves; and two Russian-Jewish émigré scientists who built a monster computer in their cramped apartment to puzzle out patterns in the value of pi. Preston’s essay on the destruction of large swaths of eastern U.S. forests by insect parasites accidentally brought into the country from abroad is the shortest but most compelling. Preston might have done more to update his pieces; for example, the Marburg virus was found in bats last year, supporting his hypothesis that they are the reservoir for Ebola. But Preston’s fans will enjoy his showing how few degrees of separation there are between far-flung areas of scientific endeavors. Illus.
Seattle Times
"Compelling . . . stories of high scientific adventure."
Denver Post
"[Preston's] stories sparkle with images of stark beauty and darkness; mature reflections about the complex worlds we all occupy."
USA Today
"With his 1994 sensation The Hot Zone, science writer Richard Preston terrified millions. . . . In his new book, Panic in Level 4, he continues to probe nature's stranger side."
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