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A comprehensive history of cancer – one of the greatest enemies of medical progress – and an insight into its effects and potential cures, by a leading expert on the illness. In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out 'war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge. Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.
A comprehensive history of cancer – one of the greatest enemies of medical progress – and an insight into its effects and potential cures, by a leading expert on the illness. In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out 'war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge. Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.
Due to publisher restrictions the library cannot purchase additional copies of this title, and we apologize if there is a long waiting list. Be sure to check for other copies, because there may be other editions available.
Due to publisher restrictions the library cannot purchase additional copies of this title, and we apologize if there is a long waiting list. Be sure to check for other copies, because there may be other editions available.
Siddhartha Mukherjee M.D., Ph.D., is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a cancer physician at the CU/NYU Presbyterian Hospital. He has published articles in Nature, New England Journal of Medicine, Neuron, the Journal of Clinical Investigation, The New York Times, and The New Republic. He lives in New York with his wife and daughter.
Reviews-
Mukherjee's sweeping biography of cancer stretches from its earliest mentions in the historical record to the latest in treatments and covers many advancements and missteps along the way. Although Stephen Hoye's narration is not immediately striking, it complements Mukherjee's work well. Hoye presents even the more complicated medical procedures with a clarity of speech that allows for easy understanding by any listener, even one not well versed in the science of cancer. This is an ambitious work but one that is very accessible and is made even more so by Hoye's narration. J.L.K. (c) AudioFile 2010, Portland, Maine
February 7, 2011 Mukherjee's magisterial history of cancer research is poorly served by Stephen Hoye's impersonal, tone-deaf narration. Mukherjee is a practicing oncologist, and his is a deeply personal account, replete with stories of his own patients and practice, that begs for an intimate reading. But Hoye is pedantic, dry, stentorian—everything that this book isn't—and his newscaster's delivery cannot convey the author's compassion for his patients or the suspense and thrill of scientific discovery that the book so brilliantly describes. A Scribner hardcover.
Starred review from September 27, 2010 Mukherjee's debut book is a sweeping epic of obsession, brilliant researchers, dramatic new treatments, euphoric success and tragic failure, and the relentless battle by scientists and patients alike against an equally relentless, wily, and elusive enemy. From the first chemotherapy developed from textile dyes to the possibilities emerging from our understanding of cancer cells, Mukherjee shapes a massive amount of history into a coherent story with a roller-coaster trajectory: the discovery of a new treatment—surgery, radiation, chemotherapy—followed by the notion that if a little is good, more must be better, ending in disfiguring radical mastectomy and multidrug chemo so toxic the treatment ended up being almost worse than the disease. The first part of the book is driven by the obsession of Sidney Farber and philanthropist Mary Lasker to find a unitary cure for all cancers. (Farber developed the first successful chemotherapy for childhood leukemia.) The last and most exciting part is driven by the race of brilliant, maverick scientists to understand how cells become cancerous. Each new discovery was small, but as Mukherjee, a Columbia professor of medicine, writes, "Incremental advances can add up to transformative changes." Mukherjee's formidable intelligence and compassion produce a stunning account of the effort to disrobe the "emperor of maladies."
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Mukherjee's sweeping biography of cancer stretches from its earliest mentions in the historical record to the latest in treatments and covers many advancements and missteps along the way. Although Stephen Hoye's narration is not immediately striking, it complements Mukherjee's work well. Hoye presents even the more complicated medical procedures with a clarity of speech that allows for easy understanding by any listener, even one not well versed in the science of cancer. This is an ambitious work but one that is very accessible and is made even more so by Hoye's narration. J.L.K. (c) AudioFile 2010, Portland, Maine
