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Magic Pill
Cover of Magic Pill
Magic Pill
The Extraordinary Benefits and Disturbing Risks of the New Weight-Loss Drugs
Borrow Borrow
The bestselling author of Lost Connections and Stolen Focus offers a revelatory look at the new drugs transforming weight loss as we know it—from his personal experience on Ozempic to our ability to heal our society’s dysfunctional relationship with food, weight, and our bodies.
In January 2023, Johann Hari started to inject himself once a week with Ozempic, one of the new drugs that produces significant weight loss. He wasn’t alone—some predictions suggest that in a few years, a quarter of the U.S. population will be taking these drugs. While around 80 percent of diets fail, someone taking one of the new drugs will lose up to a quarter of their body weight in six months. To the drugs’ defenders, here is a moment of liberation from a condition that massively increases your chances of diabetes, cancer, and an early death. 
Still, Hari was wildly conflicted. Can these drugs really be as good as they sound? Are they a magic solution—or a magic trick? Finding the answer to this high-stakes question led him on a journey from Iceland to Minneapolis to Tokyo, and to interview the leading experts in the world on these questions. He found that along with the drug’s massive benefits come twelve significant potential risks. 
He also found that these drugs radically challenge what we think we know about shame, willpower, and healing. What do they reveal about the nature of obesity itself? What psychological issues begin to emerge when our eating patterns are suddenly disrupted? Are the drugs a liberation or a further symptom of our deeply dysfunctional relationship with food? 
These drugs are about to change our world, for better and for worse. Everybody needs to understand how they work—scientifically, emotionally, and culturally. MAGIC PILL is an essential guide to the revolution that has already begun, and which one leading expert argues will be as transformative as the invention of the smartphone.
* This audiobook edition contains a downloadable PDF with additional resources and endnotes.
The bestselling author of Lost Connections and Stolen Focus offers a revelatory look at the new drugs transforming weight loss as we know it—from his personal experience on Ozempic to our ability to heal our society’s dysfunctional relationship with food, weight, and our bodies.
In January 2023, Johann Hari started to inject himself once a week with Ozempic, one of the new drugs that produces significant weight loss. He wasn’t alone—some predictions suggest that in a few years, a quarter of the U.S. population will be taking these drugs. While around 80 percent of diets fail, someone taking one of the new drugs will lose up to a quarter of their body weight in six months. To the drugs’ defenders, here is a moment of liberation from a condition that massively increases your chances of diabetes, cancer, and an early death. 
Still, Hari was wildly conflicted. Can these drugs really be as good as they sound? Are they a magic solution—or a magic trick? Finding the answer to this high-stakes question led him on a journey from Iceland to Minneapolis to Tokyo, and to interview the leading experts in the world on these questions. He found that along with the drug’s massive benefits come twelve significant potential risks. 
He also found that these drugs radically challenge what we think we know about shame, willpower, and healing. What do they reveal about the nature of obesity itself? What psychological issues begin to emerge when our eating patterns are suddenly disrupted? Are the drugs a liberation or a further symptom of our deeply dysfunctional relationship with food? 
These drugs are about to change our world, for better and for worse. Everybody needs to understand how they work—scientifically, emotionally, and culturally. MAGIC PILL is an essential guide to the revolution that has already begun, and which one leading expert argues will be as transformative as the invention of the smartphone.
* This audiobook edition contains a downloadable PDF with additional resources and endnotes.
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  • From the cover Chapter 1

    Finding the Treasure Chest


    How the drugs work

    I opened my eyes and immediately felt that something was off. Thwacking my alarm clock into silence, I lay there for five minutes, trying to figure out what it was. It was two days since I had started taking Ozempic. I felt mildly nauseous, but it was not severe—if it had happened on a normal day, it wouldn’t have stopped me from doing anything. So that wasn’t it. It took me a while to realize what it was. I always wake up ravenously hungry, but on that morning, I had no appetite at all. It was gone.

    I got out of bed and, on autopilot, went through my normal morning routine. I left my flat and went to a local café run by a Brazilian woman named Tatiana, where my order is always the same: a large, toasted bread roll, filled with chicken and mayonnaise. As I sat there reading the newspapers, the food was placed in front of me, and I looked at it. I felt like I was looking at a block of wood. I took a bite. It tasted fine. Normal. I took three or four more bites, and I felt full. I left almost all of it on the plate. As I hurried out, Tatiana called after me, “Are you sick?”

    I went to my office and wrote for three hours. Normally, by noon, I would have a snack, something small and sugary, and then at about 1 p.m. would go down the street to a local Turkish café for lunch. It got to 2 p.m. and I wasn’t hungry. Again, my sense of routine kicked in, and again, I went to the café and asked for my standard order, a large Mediterranean lamb with rice and bread. I managed to eat a third of it. It seemed to me for the first time to be incredibly salty, like I was drinking seawater.

    I wrote some more, and at 7 p.m. I left my office to go and meet a friend in Camden Market, one of my favorite parts of London. We walked between the stalls, staring at food from every part of the world. Normally, I could stuff my face from three different stalls, but that night, I had no hunger. I couldn’t even manage a few mouthfuls. I went home, feeling exhausted, and went to sleep at the unprecedentedly early time of 9 p.m.

    As that first week passed, it felt like the shutters had come down on my appetite, and now only tiny peeks of light could get through. I was about 80 percent less hungry than I normally am. The sense of mild nausea kept stirring and passing. When I got on the bus or in a car, I felt a kind of exaggerated travel sickness. Whenever I ate, I became full startlingly fast. The best way I can describe it is to ask you to imagine that you have just eaten a full Christmas dinner with all the trimmings, and then somebody popped up and offered you a whole new meal to get started on. Some people say Ozempic makes them find food disgusting. To me, it made food, beyond small quantities, feel unfeasible.

    On the fifth night, a friend came by to watch a movie, and we flicked through Uber Eats. The app suggested all my usual haunts. I realized I couldn’t eat any of this food now. Instead, she got a kebab, and I had a bowl of vegetable soup. On the sixth day, I took my godsons out, and they wanted to go into McDonald’s. When they got Happy Meals and I got nothing at all, one of them said suspiciously: “Who are you and what have you done with Johann Hari?”

    I wanted to understand what was happening to my body. I figured that the best people to educate me were the scientists who made the key discoveries that led to the development of Ozempic and the other new weight-loss drugs. So I began to track many of them down and interview them, along with many other key scientists working in the field....
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Magic Pill
Magic Pill
The Extraordinary Benefits and Disturbing Risks of the New Weight-Loss Drugs
Johann Hari
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